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Paradox of PEGylation in fabricating hybrid nanoparticle-based nicotine vaccines

Polyethylene glycol (PEG) has long been used in the nanoparticle-based drug or vaccine delivery platforms. In this study nano-nicotine vaccines (NanoNicVac) were PEGylated to different degrees to investigate the impact of PEG on the immunological efficacy of the vaccine. Hybrid nanoparticles with va...

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Detalles Bibliográficos
Publicado en:Biomaterials
Main Authors: Hu, Yun, Zhao, Zongmin, Harmon, Theresa, Pentel, Paul R, Ehrich, Marion, Zhang, Chenming
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203448/
https://ncbi.nlm.nih.gov/pubmed/30107271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.08.015
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