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Efficient cationic lipid-mediated delivery of antisense oligonucleotides into eukaryotic cells: down-regulation of the corticotropin-releasing factor receptor

Oligonucleotides (ODNs) can be employed as effective gene-specific regulators. However, before ODNs can reach their targets, several physical barriers have to be overcome, as although ODNs may pass cell membranes, most become sequestered in endocytic compartments. Accordingly, sophisticated strategi...

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Detalhes bibliográficos
Main Authors: Shi, Fuxin, Nomden, Anita, Oberle, Volker, Engberts, Jan. B. F. N., Hoekstra, Dick
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55445/
https://ncbi.nlm.nih.gov/pubmed/11353077
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