Efficient cationic lipid-mediated delivery of antisense oligonucleotides into eukaryotic cells: down-regulation of the corticotropin-releasing factor receptor

Oligonucleotides (ODNs) can be employed as effective gene-specific regulators. However, before ODNs can reach their targets, several physical barriers have to be overcome, as although ODNs may pass cell membranes, most become sequestered in endocytic compartments. Accordingly, sophisticated strategi...

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Hlavní autoři: Shi, Fuxin, Nomden, Anita, Oberle, Volker, Engberts, Jan. B. F. N., Hoekstra, Dick
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC55445/
https://ncbi.nlm.nih.gov/pubmed/11353077
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