BMTP-11 is active in preclinical models of human osteosarcoma and a candidate targeted drug for clinical translation

Osteosarcoma occurs predominantly in children and young adults. High-grade tumors require multidisciplinary treatment consisting of chemotherapy in the neoadjuvant and adjuvant settings, along with surgical intervention. Despite this approach, death from respiratory failure secondary to the developm...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Lewis, Valerae O., Devarajan, Eswaran, Cardó-Vila, Marina, Thomas, Dafydd G., Kleinerman, Eugenie S., Marchiò, Serena, Sidman, Richard L., Pasqualini, Renata, Arap, Wadih
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2017
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544306/
https://ncbi.nlm.nih.gov/pubmed/28698375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704173114
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