Aerosol Therapy for the Treatment of Osteosarcoma Lung Metastases: Targeting the Fas/FasL Pathway and Rationale for the Use of Gemcitabine

Por Gordon, Nancy, Kleinerman, Eugenie S.
Publicado em 2010

Tumor Vessel Development and Expansion in Ewing's Sarcoma: A Review of the Vasculogenesis Process and Clinical Trials with Vascular-Targeting Agents

Por Stewart, Keri S., Kleinerman, Eugenie S.
Publicado em 2011

Epigenetic Regulation of Apoptosis and Cell Cycle in Osteosarcoma

Por Rao-Bindal, Krithi, Kleinerman, Eugenie S.
Publicado em 2011

SDF-1α induces PDGF- B expression and the differentiation of bone marrow cells into pericytes

Por Hamdan, Randala, Zhou, Zhichao, Kleinerman, Eugenie S.
Publicado em 2011

Blocking SDF-1α/CXCR4 downregulates PDGF-B and inhibits bone marrow derived pericyte differentiation and tumor vascular expansion in Ewing’s tumors

Por Hamdan, Randala, Zhou, Zhichao, Kleinerman, Eugenie S.
Publicado em 2013

EWS-FLI-1 regulates the neuronal repressor gene REST, which controls Ewing sarcoma growth and vascular morphology

Por Zhou, Zhichao, Yu, Ling, Kleinerman, Eugenie S.
Publicado em 2014

Combination of NK cells therapy and oral administration of entinostat as an approach for osteosarcoma lung metastasis treatment

Por Kiany, Simin, Yu, Ling, Kleinerman, Eugenie S
Publicado no J Immunother Cancer (2015)

Fas Expression in Metastatic Osteosarcoma Cells Is Not Regulated by CpG Island Methylation

Por Huang, Gangxiong, Koshkina, Nadezhda V., Kleinerman, Eugenie S.
Publicado em 2009

Murine Bone Marrow Derived Mesenchymal Stem Cells as Vehicles for IL-12 Gene Delivery into Ewing’s Sarcoma Tumors

Por Duan, Xiaoping, Guan, Hui, Cao, Ying, Kleinerman, Eugenie S.
Publicado em 2009

Effect of the HDAC inhibitor SNDX-275 on Fas signaling in osteosarcoma cells and the feasibility of its topical application for the treatment of osteosarcoma lung metastases

Por Koshkina, Nadezhda V., Rao-Bindal, Krithi, Kleinerman, Eugenie S.
Publicado em 2011

CAPER-α alternative splicing regulates the expression of VEGF(165) in Ewing’s sarcoma cells

Por Huang, Gangxiong, Zhou, Zhichao, Wang, Hua, Kleinerman, Eugenie S.
Publicado em 2011

Promoting NK cell trafficking to improve therapeutic effect of NK cell therapy on osteosarcoma

Por Yang, Yuanzheng, Gordon, Nancy, Kleinerman, Eugenie S, Huang, Gangxiong
Publicado no J Immunother Cancer (2015)

VEGF(165) is necessary to the metastatic potential of Fas(−) osteosarcoma cells but will not rescue the Fas(+) cells.

Por Jia, Shu-Fang, Guan, Hui, Duan, Xiaoping, Kleinerman, Eugenie S.
Publicado em 2008

Bone marrow cells participate in tumor vessel formation that supports the growth of Ewing’s sarcoma in the lung

Por Zhou, Zhichao, Stewart, Keri Schadler, Yu, Ling, Kleinerman, Eugenie S.
Publicado em 2010

Immune modulation through targeting PD-1/PDL-1 signaling pathway for the treatment of osteosarcoma lung metastastasis

Por Dhupkar, Pooja M, Yu, Ling, Gordon, Nancy, Kleinerman, Eugenie S
Publicado no J Immunother Cancer (2015)

VEGF(165) promotes the osteolytic bone destruction of Ewing's sarcoma tumors by upregulating RANKL

Por Guan, Hui, Zhou, Zhichao, Cao, Ying, Duan, Xiaoping, Kleinerman, Eugenie S.
Publicado em 2009

miR-20a encoded by the miR-17-92 cluster increases the metastatic potential of osteosarcoma cells by regulating Fas expression

Por Huang, Gangxiong, Nishimoto, Kazumasa, Zhou, Zhichao, Hughes, Dennis, Kleinerman, Eugenie S.
Publicado em 2011

The Histone Deacetylase Inhibitor, MS-275 (Entinostat), Downregulates c-FLIP, Sensitizes Osteosarcoma Cells to FasL, and Induces the Regression of Osteosarcoma Lung Metastases

Por Rao-Bindal, Krithi, Koshkina, Nadezhda V., Stewart, John, Kleinerman, Eugenie S.
Publicado em 2013

Expression of c-FLIP in pulmonary metastases in osteosarcoma patients and human xenografts

Por Rao-Bindal, Krithi, Rao, Chethan K., Yu, Ling, Kleinerman, Eugenie S.
Publicado em 2012

Bone Marrow Subsets Differentiate into Endothelial Cells and Pericytes Contributing to Ewing’s Tumor Vessels

Por Reddy, Krishna, Zhou, Zhichao, Schadler, Keri, Jia, Shu-Fang, Kleinerman, Eugenie S.
Publicado em 2008