Blocking SDF-1α/CXCR4 downregulates PDGF-B and inhibits bone marrow derived pericyte differentiation and tumor vascular expansion in Ewing’s tumors

Eitemau Tebyg

• SDF-1α induces PDGF- B expression and the differentiation of bone marrow cells into pericytes
  gan: Hamdan, Randala, et al.
  Cyhoeddwyd: (2011)
• Bone Marrow Subsets Differentiate into Endothelial Cells and Pericytes Contributing to Ewing’s Tumor Vessels
  gan: Reddy, Krishna, et al.
  Cyhoeddwyd: (2008)
• VEGF(165) expression in the tumor microenvironment influences the differentiation of bone marrow-derived pericytes that contribute to the Ewing’s sarcoma vasculature
  gan: Reddy, Krishna, et al.
  Cyhoeddwyd: (2008)
• Bone marrow cells participate in tumor vessel formation that supports the growth of Ewing’s sarcoma in the lung
  gan: Zhou, Zhichao, et al.
  Cyhoeddwyd: (2010)
• SDF-1 Stimulates Vasculogenesis and Enhances Ewing’s Sarcoma Tumor Growth in the Absence of VEGF
  gan: Reddy, Krishna, et al.
  Cyhoeddwyd: (2008)