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SDF-1α induces PDGF- B expression and the differentiation of bone marrow cells into pericytes

Platelet derived growth factor B (PDGF-B) and its receptor, PDGFR-β, play a critical role in pericyte maturation; however, the mechanisms by which PDGF-B is up-regulated in the tumor microenvironment remain unclear. We previously demonstrated that up-regulating stromal-derived factor, SDF-1α, in vas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hamdan, Randala, Zhou, Zhichao, Kleinerman, Eugenie S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219839/
https://ncbi.nlm.nih.gov/pubmed/21911740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0190
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