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EWS-FLI-1 regulates the neuronal repressor gene REST, which controls Ewing sarcoma growth and vascular morphology

BACKGROUND: RE1-silencing transcription factor (REST), a neuronal repressor gene, regulates neuronal stem cell differentiation. Ewing sarcoma may originate from neural crest cells. We investigated whether REST plays a role in the growth of this tumor. METHODS: REST expression was determined by Weste...

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Hlavní autoři: Zhou, Zhichao, Yu, Ling, Kleinerman, Eugenie S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969734/
https://ncbi.nlm.nih.gov/pubmed/24415532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28555
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