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Murine Bone Marrow Derived Mesenchymal Stem Cells as Vehicles for IL-12 Gene Delivery into Ewing’s Sarcoma Tumors

BACKGROUND: This study evaluated the therapeutic efficacy of interleukin 12 (IL-12) gene therapy in Ewing’s sarcoma and whether murine mesenchymal stem cells (MSCs) could serve as vehicles for IL-12 gene delivery. METHODS: MSCs were isolated from murine bone marrow cells. Cells were phenotyped using...

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Detalhes bibliográficos
Main Authors: Duan, Xiaoping, Guan, Hui, Cao, Ying, Kleinerman, Eugenie S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652505/
https://ncbi.nlm.nih.gov/pubmed/19051291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24013
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