BMTP-11 is active in preclinical models of human osteosarcoma and a candidate targeted drug for clinical translation

Osteosarcoma occurs predominantly in children and young adults. High-grade tumors require multidisciplinary treatment consisting of chemotherapy in the neoadjuvant and adjuvant settings, along with surgical intervention. Despite this approach, death from respiratory failure secondary to the developm...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Lewis, Valerae O., Devarajan, Eswaran, Cardó-Vila, Marina, Thomas, Dafydd G., Kleinerman, Eugenie S., Marchiò, Serena, Sidman, Richard L., Pasqualini, Renata, Arap, Wadih
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2017
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544306/
https://ncbi.nlm.nih.gov/pubmed/28698375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704173114
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