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Analyses of PDE-regulated phosphoproteomes reveal unique and specific cAMP-signaling modules in T cells
Specific functions for different cyclic nucleotide phosphodiesterases (PDEs) have not yet been identified in most cell types. Conventional approaches to study PDE function typically rely on measurements of global cAMP, general increases in cAMP-dependent protein kinase (PKA), or the activity of exch...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5544305/ https://ncbi.nlm.nih.gov/pubmed/28634298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703939114 |
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