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SCAP/SREBP pathway is required for the full steroidogenic response to cyclic AMP
Luteinizing hormone (LH) stimulates steroidogenesis largely through a surge in cyclic AMP (cAMP). Steroidogenic rates are also critically dependent on the availability of cholesterol at mitochondrial sites of synthesis. This cholesterol is provided by cellular uptake of lipoproteins, mobilization of...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5035853/ https://ncbi.nlm.nih.gov/pubmed/27601673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611424113 |
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