Phosphoproteomic Analysis as an Approach for Understanding Molecular Mechanisms of cAMP-Dependent Actions

In recent years, highly sensitive mass spectrometry–based phosphoproteomic analysis is beginning to be applied to identification of protein kinase substrates altered downstream of increased cAMP. Such studies identify a very large number of phosphorylation sites regulated in response to increased cA...

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Bibliographic Details
Published in:Mol Pharmacol
Main Authors: Beavo, Joseph A., Golkowski, Martin, Shimizu-Albergine, Masami, Beltejar, Michael-Claude, Bornfeldt, Karin E., Ong, Shao-En
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2021
Subjects:
Special Section on Phosphoproteomic Analysis of G Protein-Coupled Pathways - Axelrod Symposium—Minireview
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058506/
https://ncbi.nlm.nih.gov/pubmed/33574048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/molpharm.120.000197
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