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Kinobead/LC-MS phosphokinome profiling enables rapid analyses of kinase-dependent cell signaling networks

Kinase-catalyzed protein phosphorylation is fundamental to eukaryotic signal transduction, regulating most cellular processes. Kinases are frequently dysregulated in cancer, inflammation and degenerative diseases, and because they can be inhibited with small molecules, they became important drug tar...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Golkowski, Martin, Vidadala, Venkata Narayana, Lau, Ho-Tak, Shoemaker, Anna, Shimizu-Albergine, Masami, Beavo, Joseph, Maly, Dustin J., Ong, Shao-En
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7537592/
https://ncbi.nlm.nih.gov/pubmed/32037842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.9b00742
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