Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system

Hedgehog (Hh) signaling in vertebrates depends on primary cilia. Upon stimulation, Hh pathway components, including Gli transcription factors, accumulate at primary cilia to transduce the Hh signal, but the mechanisms underlying their ciliary targeting remains largely unknown. Here, we show that the...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Biol
Egile Nagusiak: Han, Yuhong, Xiong, Yue, Shi, Xuanming, Wu, Jiang, Zhao, Yun, Jiang, Jin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544186/
https://ncbi.nlm.nih.gov/pubmed/28777795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2002063
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