טוען...
Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS
Fused in sarcoma (FUS) is a nuclear protein that carries a proline-tyrosine nuclear localization signal (PY-NLS) and is imported into the nucleus via Transportin (TRN). Defects in nuclear import of FUS have been implicated in neurodegeneration, since mutations in the PY-NLS of FUS cause amyotrophic...
שמור ב:
| Main Authors: | , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
European Molecular Biology Organization
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501225/ https://ncbi.nlm.nih.gov/pubmed/22968170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.261 |
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