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ULK2 Ser 1027 Phosphorylation by PKA Regulates Its Nuclear Localization Occurring through Karyopherin Beta 2 Recognition of a PY-NLS Motif

Uncoordinated 51-like kinase 2 (ULK2), a member of the serine/threonine kinase family, plays an essential role in the regulation of autophagy in mammalian cells. Given the role of autophagy in normal cellular homeostasis and in multiple diseases, improved mechanistic insight into this process may re...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Shin, Sung Hwa, Lee, Eun Jeoung, Chun, Jaesun, Hyun, Sunghee, Kang, Sang Sun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460075/
https://ncbi.nlm.nih.gov/pubmed/26052940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127784
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