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ULK2 Ser 1027 Phosphorylation by PKA Regulates Its Nuclear Localization Occurring through Karyopherin Beta 2 Recognition of a PY-NLS Motif

Uncoordinated 51-like kinase 2 (ULK2), a member of the serine/threonine kinase family, plays an essential role in the regulation of autophagy in mammalian cells. Given the role of autophagy in normal cellular homeostasis and in multiple diseases, improved mechanistic insight into this process may re...

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Pubblicato in:PLoS One
Autori principali: Shin, Sung Hwa, Lee, Eun Jeoung, Chun, Jaesun, Hyun, Sunghee, Kang, Sang Sun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460075/
https://ncbi.nlm.nih.gov/pubmed/26052940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127784
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