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Target identification and mechanism of action in chemical biology and drug discovery

Target-identification and mechanism-of-action studies have important roles in small-molecule probe and drug discovery. Biological and technological advances have resulted in the increasing use of cell-based assays to discover new biologically active small molecules. Such studies allow small-molecule...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Schenone, Monica, Dančík, Vlado, Wagner, Bridget K, Clemons, Paul A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543995/
https://ncbi.nlm.nih.gov/pubmed/23508189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1199
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