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Mechanism of Action and Target Identification: A Matter of Timing in Drug Discovery

Two opposing viewpoints are held regarding the need for understanding a drug's molecular target and mechanism of action. One extreme viewpoint is that it is unnecessary, because, after all, there are many beneficial drugs in use for which the target and mechanism of action remain unknown. A sec...

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Опубликовано в: :iScience
Главный автор: Davis, Ronald L.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479624/
https://ncbi.nlm.nih.gov/pubmed/32891054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101487
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