Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation

GPCR expression was intensively studied in bulk cDNA of leukocyte populations, but limited data are available with respect to expression in individual cells. Here, we show a microfluidic-based single-cell GPCR expression analysis in primary T cells, myeloid cells, and endothelial cells under naive c...

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Pubblicato in:JCI Insight
Autori principali: Tischner, Denise, Grimm, Myriam, Kaur, Harmandeep, Staudenraus, Daniel, Carvalho, Jorge, Looso, Mario, Günther, Stefan, Wanke, Florian, Moos, Sonja, Siller, Nelly, Breuer, Johanna, Schwab, Nicholas, Zipp, Frauke, Waisman, Ari, Kurschus, Florian C., Offermanns, Stefan, Wettschureck, Nina
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543912/
https://ncbi.nlm.nih.gov/pubmed/28768912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95063
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