Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation

GPCR expression was intensively studied in bulk cDNA of leukocyte populations, but limited data are available with respect to expression in individual cells. Here, we show a microfluidic-based single-cell GPCR expression analysis in primary T cells, myeloid cells, and endothelial cells under naive c...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Tischner, Denise, Grimm, Myriam, Kaur, Harmandeep, Staudenraus, Daniel, Carvalho, Jorge, Looso, Mario, Günther, Stefan, Wanke, Florian, Moos, Sonja, Siller, Nelly, Breuer, Johanna, Schwab, Nicholas, Zipp, Frauke, Waisman, Ari, Kurschus, Florian C., Offermanns, Stefan, Wettschureck, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543912/
https://ncbi.nlm.nih.gov/pubmed/28768912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95063
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