Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system

G-protein-coupled receptor (GPCR) expression is extensively studied in bulk cDNA, but heterogeneity and functional patterning of GPCR expression in individual vascular cells is poorly understood. Here, we perform a microfluidic-based single-cell GPCR expression analysis in primary smooth muscle cell...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Kaur, H., Carvalho, J., Looso, M., Singh, P., Chennupati, R., Preussner, J., Günther, S., Albarrán-Juárez, J., Tischner, D., Classen, S., Offermanns, S., Wettschureck, N.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481776/
https://ncbi.nlm.nih.gov/pubmed/28621310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15700
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