Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood–brain barrier

The proinflammatory cytokine interleukin 1 (IL-1) is crucially involved in the pathogenesis of multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE). Herein, we studied the role of IL-1 signaling in blood–brain barrier (BBB) endothelial cells (ECs), astrocytes...

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Xehetasun bibliografikoak
Argitaratua izan da:Acta Neuropathol
Egile Nagusiak: Hauptmann, Judith, Johann, Lisa, Marini, Federico, Kitic, Maja, Colombo, Elisa, Mufazalov, Ilgiz A., Krueger, Martin, Karram, Khalad, Moos, Sonja, Wanke, Florian, Kurschus, Florian C., Klein, Matthias, Cardoso, Silvia, Strauß, Judith, Bolisetty, Subhashini, Lühder, Fred, Schwaninger, Markus, Binder, Harald, Bechman, Ingo, Bopp, Tobias, Agarwal, Anupam, Soares, Miguel P., Regen, Tommy, Waisman, Ari
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Berlin Heidelberg 2020
Gaiak:
Original Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498485/
https://ncbi.nlm.nih.gov/pubmed/32651669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-020-02187-x
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