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IL‐1 signaling is critical for expansion but not generation of autoreactive GM‐CSF (+) Th17 cells

Interleukin‐1 (IL‐1) is implicated in numerous pathologies, including multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE). However, the exact mechanism by which IL‐1 is involved in the generation of pathogenic T cells and in disease development remains largely unk...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Mufazalov, Ilgiz A, Schelmbauer, Carsten, Regen, Tommy, Kuschmann, Janina, Wanke, Florian, Gabriel, Laureen A, Hauptmann, Judith, Müller, Werner, Pinteaux, Emmanuel, Kurschus, Florian C, Waisman, Ari
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210124/
https://ncbi.nlm.nih.gov/pubmed/27827809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694615
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