IL‐1 signaling is critical for expansion but not generation of autoreactive GM‐CSF (+) Th17 cells

Interleukin‐1 (IL‐1) is implicated in numerous pathologies, including multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE). However, the exact mechanism by which IL‐1 is involved in the generation of pathogenic T cells and in disease development remains largely unk...

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Pubblicato in:EMBO J
Autori principali: Mufazalov, Ilgiz A, Schelmbauer, Carsten, Regen, Tommy, Kuschmann, Janina, Wanke, Florian, Gabriel, Laureen A, Hauptmann, Judith, Müller, Werner, Pinteaux, Emmanuel, Kurschus, Florian C, Waisman, Ari
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210124/
https://ncbi.nlm.nih.gov/pubmed/27827809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694615
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