IL‐1 signaling is critical for expansion but not generation of autoreactive GM‐CSF (+) Th17 cells

Interleukin‐1 (IL‐1) is implicated in numerous pathologies, including multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE). However, the exact mechanism by which IL‐1 is involved in the generation of pathogenic T cells and in disease development remains largely unk...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Mufazalov, Ilgiz A, Schelmbauer, Carsten, Regen, Tommy, Kuschmann, Janina, Wanke, Florian, Gabriel, Laureen A, Hauptmann, Judith, Müller, Werner, Pinteaux, Emmanuel, Kurschus, Florian C, Waisman, Ari
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210124/
https://ncbi.nlm.nih.gov/pubmed/27827809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694615
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