IL‐1 signaling is critical for expansion but not generation of autoreactive GM‐CSF (+) Th17 cells

Interleukin‐1 (IL‐1) is implicated in numerous pathologies, including multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE). However, the exact mechanism by which IL‐1 is involved in the generation of pathogenic T cells and in disease development remains largely unk...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Mufazalov, Ilgiz A, Schelmbauer, Carsten, Regen, Tommy, Kuschmann, Janina, Wanke, Florian, Gabriel, Laureen A, Hauptmann, Judith, Müller, Werner, Pinteaux, Emmanuel, Kurschus, Florian C, Waisman, Ari
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210124/
https://ncbi.nlm.nih.gov/pubmed/27827809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694615
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