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IL‐1 signaling is critical for expansion but not generation of autoreactive GM‐CSF (+) Th17 cells

Interleukin‐1 (IL‐1) is implicated in numerous pathologies, including multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE). However, the exact mechanism by which IL‐1 is involved in the generation of pathogenic T cells and in disease development remains largely unk...

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Библиографические подробности
Опубликовано в: :EMBO J
Главные авторы: Mufazalov, Ilgiz A, Schelmbauer, Carsten, Regen, Tommy, Kuschmann, Janina, Wanke, Florian, Gabriel, Laureen A, Hauptmann, Judith, Müller, Werner, Pinteaux, Emmanuel, Kurschus, Florian C, Waisman, Ari
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210124/
https://ncbi.nlm.nih.gov/pubmed/27827809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694615
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