Rifaximin Exerts Beneficial Effects Independent of its Ability to Alter Microbiota Composition

OBJECTIVES: Rifaximin has clinical benefits in minimal hepatic encephalopathy (MHE) but the mechanism of action is unclear. The antibiotic-dependent and -independent effects of rifaximin need to be elucidated in the setting of MHE-associated microbiota. To assess the action of rifaximin on intestina...

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Veröffentlicht in:Clin Transl Gastroenterol
Hauptverfasser: Kang, Dae J, Kakiyama, Genta, Betrapally, Naga S, Herzog, Jeremy, Nittono, Hiroshi, Hylemon, Phillip B, Zhou, Huiping, Carroll, Ian, Yang, Jing, Gillevet, Patrick M, Jiao, Chunhua, Takei, Hajime, Pandak, William M, Iida, Takashi, Heuman, Douglas M, Fan, Sili, Fiehn, Oliver, Kurosawa, Takao, Sikaroodi, Masoumeh, Sartor, R B, Bajaj, Jasmohan S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Contributions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543406/
https://ncbi.nlm.nih.gov/pubmed/27560928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2016.44
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