Rifaximin Exerts Beneficial Effects Independent of its Ability to Alter Microbiota Composition

OBJECTIVES: Rifaximin has clinical benefits in minimal hepatic encephalopathy (MHE) but the mechanism of action is unclear. The antibiotic-dependent and -independent effects of rifaximin need to be elucidated in the setting of MHE-associated microbiota. To assess the action of rifaximin on intestina...

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Detalhes bibliográficos
Publicado no:Clin Transl Gastroenterol
Main Authors: Kang, Dae J, Kakiyama, Genta, Betrapally, Naga S, Herzog, Jeremy, Nittono, Hiroshi, Hylemon, Phillip B, Zhou, Huiping, Carroll, Ian, Yang, Jing, Gillevet, Patrick M, Jiao, Chunhua, Takei, Hajime, Pandak, William M, Iida, Takashi, Heuman, Douglas M, Fan, Sili, Fiehn, Oliver, Kurosawa, Takao, Sikaroodi, Masoumeh, Sartor, R B, Bajaj, Jasmohan S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Contributions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543406/
https://ncbi.nlm.nih.gov/pubmed/27560928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2016.44
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