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Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1
Hypoxia-inducible factor 1 (HIF-1) activates the transcription of genes encoding proteins that enable cells to adapt to reduced O(2) availability. Proteins encoded by HIF-1 target genes play a central role in mediating physiological processes that are dysregulated in cancer and heart disease. These...
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| Publicado no: | Sci Signal |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5541497/ https://ncbi.nlm.nih.gov/pubmed/27245613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf0583 |
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