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Targeting Hypoxia-Inducible Factor 1 to Stimulate Tissue Vascularization
When tissue perfusion is impaired, the resulting reduction in O(2) availability activates hypoxia-inducible factor 1 (HIF-1), which mediates increased transcription of genes encoding multiple angiogenic factors including vascular endothelial growth factor, stromal derived factor 1, placental growth...
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| Publicado no: | J Investig Med |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4636970/ https://ncbi.nlm.nih.gov/pubmed/25955799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JIM.0000000000000206 |
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