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Hypoxia-Inducible Factor 1 and Cardiovascular Disease

Cardiac function is required for blood circulation and systemic oxygen delivery. However, the heart has intrinsic oxygen demands that must be met to maintain effective contractility. Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that functions as a master regulator of oxygen homeostas...

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Detalhes bibliográficos
Publicado no:Annu Rev Physiol
Autor principal: Semenza, Gregg L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696033/
https://ncbi.nlm.nih.gov/pubmed/23988176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-021113-170322
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