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Hypoxia-Inducible Factor 1: Regulator of Mitochondrial Metabolism and Mediator of Ischemic Preconditioning
Hypoxia-inducible factor 1 (HIF-1) mediates adaptive responses to reduced oxygen availability by regulating gene expression. A critical cell-autonomous adaptive response to chronic hypoxia controlled by HIF-1 is reduced mitochondrial mass and/or metabolism. Exposure of HIF-1-deficient fibroblasts to...
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| Natura: | Artigo |
| Lingua: | Inglês |
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2010
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3010308/ https://ncbi.nlm.nih.gov/pubmed/20732359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.08.006 |
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