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Protein S-Nitrosylation Controls Glycogen Synthase Kinase 3β Function Independent of its Phosphorylation State

RATIONALE: Glycogen synthase kinase 3β (GSK3β) is a multifunctional and constitutively active kinase known to regulate a myriad of cellular processes. The primary mechanism to regulate its function is through phosphorylation-dependent inhibition at serine-9 residue. Emerging evidence indicates that...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Wang, Sheng-Bing, Venkatraman, Vidya, Crowgey, Erin L., Liu, Ting, Fu, Zongming, Holewinski, Ronald, Ranek, Mark, Kass, David A., O’Rourke, Brian, Van Eyk, Jennifer E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047766/
https://ncbi.nlm.nih.gov/pubmed/29563102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.312789
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