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Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

Exposure of susceptible neuroblastoma N2a cells to mouse scrapie prions leads to infection, as evidenced by the continued presence of the scrapie form of the prion protein (PrP(Sc)) and infectivity after 300 or more cell doublings. We find that exposure to phosphatidylinositol-specific phospholipase...

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書誌詳細
主要な著者: Enari, Masato, Flechsig, Eckhard, Weissmann, Charles
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC55414/
https://ncbi.nlm.nih.gov/pubmed/11470893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151242598
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