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B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice
Prion replication in spleen and neuroinvasion after i.p. inoculation of mice is impaired in forms of immunodeficiency where mature B lymphocytes are lacking. In spleens of wild-type mice, infectivity is associated with B and T lymphocytes and stroma but not with circulating lymphocytes. We generated...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The National Academy of Sciences
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31174/ https://ncbi.nlm.nih.gov/pubmed/11274428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051609398 |
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