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Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

Exposure of susceptible neuroblastoma N2a cells to mouse scrapie prions leads to infection, as evidenced by the continued presence of the scrapie form of the prion protein (PrP(Sc)) and infectivity after 300 or more cell doublings. We find that exposure to phosphatidylinositol-specific phospholipase...

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Hlavní autoři: Enari, Masato, Flechsig, Eckhard, Weissmann, Charles
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC55414/
https://ncbi.nlm.nih.gov/pubmed/11470893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151242598
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