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Islet Amyloid Polypeptide Membrane Interactions: Effects of Membrane Composition
Amyloid formation by islet amyloid polypeptide (IAPP) contributes to β-cell dysfunction in type-2 diabetes. Perturbation of the β-cell membrane may contribute to IAPP induced toxicity. We examine the effects of lipid composition, salt and buffer on IAPP amyloid formation and on the ability of IAPP t...
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| Udgivet i: | Biochemistry |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5541234/ https://ncbi.nlm.nih.gov/pubmed/28054763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01016 |
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