Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma

Genomic diversity among melanoma tumors limits durable control with conventional and targeted therapies. Nevertheless, pathological activation of the ERK1/2 pathway is a linchpin tumorigenic mechanism associated with the majority of primary and recurrent disease. Therefore, we sought to identify the...

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書誌詳細
出版年:Cancer Discov
主要な著者: Eskiocak, Banu, McMillan, Elizabeth A., Mendiratta, Saurabh, Kollipara, Rahul K., Zhang, Hailei, Humphries, Caroline G., Wang, Changguang, Garcia-Rodriguez, Jose, Ding, Ming, Zaman, Aubhishek, Rosales, Tracy I., Eskiocak, Ugur, Smith, Michael, Sudderth, Jessica, Komurov, Kakajan, Deberardinis, Ralph, Wellbrock, Claudia, Davies, Michael A., Wargo, Jennifer A., Yu, Yonghao, De Brabander, Jef K., Williams, Noelle S., Chin, Lynda, Rizos, Helen, Long, Georgina, Kittler, Ralf, White, Michael A.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540806/
https://ncbi.nlm.nih.gov/pubmed/28455392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0955
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