Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma

Genomic diversity among melanoma tumors limits durable control with conventional and targeted therapies. Nevertheless, pathological activation of the ERK1/2 pathway is a linchpin tumorigenic mechanism associated with the majority of primary and recurrent disease. Therefore, we sought to identify the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Eskiocak, Banu, McMillan, Elizabeth A., Mendiratta, Saurabh, Kollipara, Rahul K., Zhang, Hailei, Humphries, Caroline G., Wang, Changguang, Garcia-Rodriguez, Jose, Ding, Ming, Zaman, Aubhishek, Rosales, Tracy I., Eskiocak, Ugur, Smith, Michael, Sudderth, Jessica, Komurov, Kakajan, Deberardinis, Ralph, Wellbrock, Claudia, Davies, Michael A., Wargo, Jennifer A., Yu, Yonghao, De Brabander, Jef K., Williams, Noelle S., Chin, Lynda, Rizos, Helen, Long, Georgina, Kittler, Ralf, White, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540806/
https://ncbi.nlm.nih.gov/pubmed/28455392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0955
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados