Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma

Genomic diversity among melanoma tumors limits durable control with conventional and targeted therapies. Nevertheless, pathological activation of the ERK1/2 pathway is a linchpin tumorigenic mechanism associated with the majority of primary and recurrent disease. Therefore, we sought to identify the...

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Xehetasun bibliografikoak
Argitaratua izan da:Cancer Discov
Egile Nagusiak: Eskiocak, Banu, McMillan, Elizabeth A., Mendiratta, Saurabh, Kollipara, Rahul K., Zhang, Hailei, Humphries, Caroline G., Wang, Changguang, Garcia-Rodriguez, Jose, Ding, Ming, Zaman, Aubhishek, Rosales, Tracy I., Eskiocak, Ugur, Smith, Michael, Sudderth, Jessica, Komurov, Kakajan, Deberardinis, Ralph, Wellbrock, Claudia, Davies, Michael A., Wargo, Jennifer A., Yu, Yonghao, De Brabander, Jef K., Williams, Noelle S., Chin, Lynda, Rizos, Helen, Long, Georgina, Kittler, Ralf, White, Michael A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540806/
https://ncbi.nlm.nih.gov/pubmed/28455392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0955
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