N-Myc induces an EZH2-mediated transcriptional program driving Neuroendocrine Prostate Cancer

The transition from castration resistant prostate adenocarcinoma (CRPC) to neuroendocrine prostate cancer (NEPC) has emerged as an important mechanism of treatment resistance. NEPC is associated with over-expression and gene amplification of MYCN (encoding N-Myc). N-Myc is an established oncogene in...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cancer Cell
Autors principals: Dardenne, Etienne, Beltran, Himisha, Benelli, Matteo, Gayvert, Kaitlyn, Berger, Adeline, Puca, Loredana, Cyrta, Joanna, Sboner, Andrea, Noorzad, Zohal, MacDonald, Theresa, Cheung, Cynthia, Yuen, Ka Shing, Gao, Dong, Chen, Yu, Eilers, Martin, Mosquera, Juan-Miguel, Robinson, Brian D., Elemento, Olivier, Rubin, Mark A., Demichelis, Francesca, Rickman, David S.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540451/
https://ncbi.nlm.nih.gov/pubmed/27728805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.09.005
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars