טוען...
Engineering humanized antibody framework sequences for optimal site-specific conjugation of cytotoxins
The prevailing techniques used to generate antibody-drug conjugates (ADCs) involve random conjugation of the linker-drug to multiple lysines or cysteines in the antibody. Engineering natural and non-natural amino acids into an antibody has been demonstrated to be an effective strategy to produce hom...
שמור ב:
| הוצא לאור ב: | MAbs |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5540084/ https://ncbi.nlm.nih.gov/pubmed/28541812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1330734 |
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