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Exosomes Facilitate Therapeutic Targeting of Oncogenic Kras in Pancreatic Cancer
The mutant form of the GTPase KRAS is a key driver of pancreatic cancer but remains a challenging therapeutic target. Exosomes, extracellular vesicles generated by all cells, are naturally present in the blood. Here we demonstrate that enhanced retention of exosomes in circulation, compared to lipos...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5538883/ https://ncbi.nlm.nih.gov/pubmed/28607485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22341 |
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