Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer

Pancreatic cancer presents with a dismal mortality rate and is in urgent need of methods for early detection with potential for timely intervention. All living cells, including cancer cells, generate exosomes. We previously discovered double stranded genomic DNA in exosomes derived from the circulat...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Yang, Sujuan, Che, Sara P. Y., Kurywchak, Paul, Tavormina, Jena L., Gansmo, Liv B., Correa de Sampaio, Pedro, Tachezy, Michael, Bockhorn, Maximilian, Gebauer, Florian, Haltom, Amanda R., Melo, Sonia A., LeBleu, Valerie S., Kalluri, Raghu
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389423/
https://ncbi.nlm.nih.gov/pubmed/28121262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1281499
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