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Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand
Mismatch repair (MMR) is one of the main systems maintaining fidelity of replication. Differences in correction of errors produced during replication of the leading and the lagging DNA strands were reported in yeast and in human cancers, but the causes of these differences remain unclear. Here, we a...
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| Udgivet i: | Genome Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5538550/ https://ncbi.nlm.nih.gov/pubmed/28512192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.219915.116 |
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