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Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand

Mismatch repair (MMR) is one of the main systems maintaining fidelity of replication. Differences in correction of errors produced during replication of the leading and the lagging DNA strands were reported in yeast and in human cancers, but the causes of these differences remain unclear. Here, we a...

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Detaylı Bibliyografya
Yayımlandı:Genome Res
Asıl Yazarlar: Andrianova, Maria A., Bazykin, Georgii A., Nikolaev, Sergey I., Seplyarskiy, Vladimir B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538550/
https://ncbi.nlm.nih.gov/pubmed/28512192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.219915.116
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