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Evolution of Local Mutation Rate and Its Determinants

Mutation rate varies along the human genome, and part of this variation is explainable by measurable local properties of the DNA molecule. Moreover, mutation rates differ between orthologous genomic regions of different species, but the drivers of this change are unclear. Here, we use data on human...

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Bibliografiske detaljer
Udgivet i:Mol Biol Evol
Main Authors: Terekhanova, Nadezhda V., Seplyarskiy, Vladimir B., Soldatov, Ruslan A., Bazykin, Georgii A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850301/
https://ncbi.nlm.nih.gov/pubmed/28138076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msx060
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