Single-cell sequencing deciphers a convergent evolution of copy number alterations from primary to circulating tumor cells

Copy number alteration (CNA) is a major contributor to genome instability, a hallmark of cancer. Here, we studied genomic alterations in single primary tumor cells and circulating tumor cells (CTCs) from the same patient. Single-nucleotide variants (SNVs) in single cells from both samples occurred s...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Gao, Yan, Ni, Xiaohui, Guo, Hua, Su, Zhe, Ba, Yi, Tong, Zhongsheng, Guo, Zhi, Yao, Xin, Chen, Xixi, Yin, Jian, Yan, Zhao, Guo, Lin, Liu, Ying, Bai, Fan, Xie, X. Sunney, Zhang, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538548/
https://ncbi.nlm.nih.gov/pubmed/28487279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.216788.116
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