Somatic copy number profiling from hepatocellular carcinoma circulating tumor cells

Somatic copy number alterations (SCNAs) are important genetic drivers of many cancers. We investigated the feasibility of obtaining SCNA profiles from circulating tumor cells (CTCs) as a molecular liquid biopsy for hepatocellular carcinoma (HCC). CTCs from ten HCC patients underwent SCNA profiling....

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Veröffentlicht in:NPJ Precis Oncol
Hauptverfasser: Court, Colin M., Hou, Shuang, Liu, Lian, Winograd, Paul, DiPardo, Benjamin J., Liu, Sean X., Chen, Pin-Jung, Zhu, Yazhen, Smalley, Matthew, Zhang, Ryan, Sadeghi, Saeed, Finn, Richard S., Kaldas, Fady M., Busuttil, Ronald W., Zhou, Xianghong J., Tseng, Hsian-Rong, Tomlinson, James S., Graeber, Thomas G., Agopian, Vatche G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331695/
https://ncbi.nlm.nih.gov/pubmed/32637655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-020-0123-0
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