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Precision oncology using a limited number of cells: optimization of whole genome amplification products for sequencing applications
BACKGROUND: Sequencing analysis of circulating tumor cells (CTCs) enables “liquid biopsy” to guide precision oncology strategies. However, this requires low-template whole genome amplification (WGA) that is prone to errors and biases from uneven amplifications. Currently, quality control (QC) method...
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| Publicado no: | BMC Cancer |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5493892/ https://ncbi.nlm.nih.gov/pubmed/28666423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3447-6 |
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