Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients

Circulating tumor cells (CTCs) enter peripheral blood from primary tumors and seed metastases. The genome sequencing of CTCs could offer noninvasive prognosis or even diagnosis, but has been hampered by low single-cell genome coverage of scarce CTCs. Here, we report the use of the recently developed...

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Detalhes bibliográficos
Main Authors: Ni, Xiaohui, Zhuo, Minglei, Su, Zhe, Duan, Jianchun, Gao, Yan, Wang, Zhijie, Zong, Chenghang, Bai, Hua, Chapman, Alec R., Zhao, Jun, Xu, Liya, An, Tongtong, Ma, Qi, Wang, Yuyan, Wu, Meina, Sun, Yu, Wang, Shuhang, Li, Zhenxiang, Yang, Xiaodan, Yong, Jun, Su, Xiao-Dong, Lu, Youyong, Bai, Fan, Xie, X. Sunney, Wang, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876226/
https://ncbi.nlm.nih.gov/pubmed/24324171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320659110
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