Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients

Circulating tumor cells (CTCs) enter peripheral blood from primary tumors and seed metastases. The genome sequencing of CTCs could offer noninvasive prognosis or even diagnosis, but has been hampered by low single-cell genome coverage of scarce CTCs. Here, we report the use of the recently developed...

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Détails bibliographiques
Auteurs principaux: Ni, Xiaohui, Zhuo, Minglei, Su, Zhe, Duan, Jianchun, Gao, Yan, Wang, Zhijie, Zong, Chenghang, Bai, Hua, Chapman, Alec R., Zhao, Jun, Xu, Liya, An, Tongtong, Ma, Qi, Wang, Yuyan, Wu, Meina, Sun, Yu, Wang, Shuhang, Li, Zhenxiang, Yang, Xiaodan, Yong, Jun, Su, Xiao-Dong, Lu, Youyong, Bai, Fan, Xie, X. Sunney, Wang, Jie
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876226/
https://ncbi.nlm.nih.gov/pubmed/24324171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320659110
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