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N-Substituted tertiary and O-substituted quaternary carbon stereogenic centers by site-, diastereo- and enantioselective vinylogous Mannich reactions

A readily accessible small-molecule phosphine, derived from commercially available starting materials such as an enantiomerically pure amino acid, serves as the precursor to a Ag-based chiral complex that can be prepared and used in situ to promote a variety of enantioselective vinylogous Mannich (E...

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Bibliographische Detailangaben
Veröffentlicht in:Tetrahedron Lett
Hauptverfasser: Silverio, Daniel L., Fu, Peng, Carswell, Emma L., Snapper, Marc L., Hoveyda, Amir H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538379/
https://ncbi.nlm.nih.gov/pubmed/28775388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2015.04.006
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